A Generation at Risk: When the baby boomers reach Golden Pond

Hogg Foundation for Mental Healt

Improving Drug Safety: The Importance of Postmarking Drug Surveillance

Improved postmarketing surveillance system may reduce the number of adverse reactions to prescription drugs that under the current system continue to rise as the number of prescriptions written in the U.S. rises

Achieving and Maintaining Cognitive Vitality With Aging

This report contains the summary results of a workshop held at Canyon Ranch Health Resort in Tucson, Arizona. Physicians and scientists shed light on the process of cognitive aging. They review current scientific and clinical knowledge of normal human cognitive aging, the biological mechanisms that underlie this process, and risk factors associated with mental decline. They make recommendations for lifestyle changes and outline a research agenda for the development of new therapies to prevent mental decline and maintain cognitive vitality

Biomarkers of Aging: From Primitive Organisms to Man

What biological changes take place as we age? Efforts by scientists to uncover the biomarkers of aging, that is, the normal phenomena of growing old, and to separate these inevitable physiologic changes from diseases and other factors.Warns that alleged "anti-aging" medicines like growth hormone injections are unprovable given current scientific knowledge

Preparing for an Aging Nation: The Need for Academic Geriatricians

According to the author of this issue brief, a strong commitment by the government to a regular stream of financial support for geriatrics would encourage medical centers to establish or expand programs, enhance their ability to attract funds from private sources, and ultimately produce a sufficient number of academic geriatricians. Given the impending retirement of the baby boom generation, this process should begin as soon as possible. This issue brief highlights the critical need for academic geriatricians and presents a realistic proposal to help address the problem

Walk to a Healthy Future

Proposes a new national commitment to walking and formation of walking partnerships and clubs to fight the epidemic of overweight Americans

DI in the outer Galaxy

We report on a deep search with the Westerbork Synthesis Radio Telescope towards the galactic anticenter for the 327 MHz hyperfine transition of DI. This is a favorable direction for a search because: (i) the HI optical depth is high due to velocity crowding; (ii) the observed molecular column density is low (implying that most of the deuterium would probably be in atomic form, rather than in HD); and (iii) the stellar reprocessing should be minimal. Our observations are about a factor of two more sensitive than previous searches for DI in this direction. We detect a low significance (about 4 sigma) feature, consistent in both amplitude and center frequency with an emission feature reported previously (Blitz & Heiles 1987). If this is the DI line, then the implied N_D/N_H of 3.9+/-1.0 x 10^-5 is comparable to the inferred pre-solar deuterium abundance. Our observation is consistent with the recent low measurements of D/H towards high-redshift Lyman-limit systems. On the other hand, if the reports of high DI abundance (about 24 x 10^-5) in such systems are confirmed, then our observations imply that even in regions of reduced star formation within the outer Galaxy, the DI abundance has been reduced by a factor of about 6 from the primordial abundance.Comment: 4 page LaTeX requires l-aa.sty and psfig.sty, 1 ps figure. Accepted for publication in A&A Letter

The Need for Drug Safety: The Older Person and Ageism

With errors in the administration of drugs and adverse reactions accounting for more than 100,000 deaths annually, Dr. Robert N. Butler, president and CEO of the ILC-USA, addresses the urgent need for clinical trials that include older adults and careful monitoring of drugs in the years following approval by the FDA

Caregiving in America

The United States is in the midst of a significant and growing caregiving crisis. About 1.4 million older Americans live in nursing homes, nearly 6 million receive care at home, and significant numbers go completely without the help they need

Removal of terrestrial DOC in aquatic ecosystems of a temperate river network

Surface waters play a potentially important role in the global carbon balance. Dissolved organic carbon (DOC) fluxes are a major transfer of terrestrial carbon to river systems, and the fate of DOC in aquatic systems is poorly constrained. We used a unique combination of spatially distributed sampling of three DOC fractions throughout a river network and modeling to quantify the net removal of terrestrial DOC during a summer base flow period. We found that aquatic reactivity of terrestrial DOC leading to net loss is low, closer to conservative chloride than to reactive nitrogen. Net removal occurred mainly from the hydrophobic organic acid fraction, while hydrophilic and transphilic acids showed no net change, indicating that partitioning of bulk DOC into different fractions is critical for understanding terrestrial DOC removal. These findings suggest that river systems may have only a modest ability to alter the amounts of terrestrial DOC delivered to coastal zones